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12 CO2 HCO3-. This effect is in accordance with in vivo studies showing that the feeding of diets supplemented with easily fermentable carbohydrates thereby increasing the intraruminal concentration of SCFA and CO2 HCO3- ; leads to an elevation of the Mg2 + absorption 8, 11 ; . In vitro experiments with isolated ruminal epithelia have confirmed these results and demonstrate that the so-called K + - or PD-insensitive component of Mg2 + uptake is stimulated specifically 23 ; . After excluding a Mg2 + 2H + antiporter as the underlying mechanism, we have hypothesized the existence of a Mg2 + -anion cotransport 36 ; . The results obtained in the high-NaCl medium, viz., 1 ; that butyrate alone is not able to stimulate Mg2 + uptake 2 ; that the rate of Mg2 + uptake is the same in HCO3--buffered media and HCO3--buffered media with additional butyrate, have led us to presume that the Mg2 + influx is coupled to HCO3- uptake via a Mg2 + -2HCO3cotransport. Such a transport system has been shown by Gnther et al. 14 ; in Yoshida ascites tumor cells. However, the existence of an Mg2 + -2HCO3- cotransport is strongly opposed by the finding that the stimulating effect of HCO3- is completely abolished after reduction of the extracellular [Cl-]. In the experiments performed by Gnther et al. 14 ; , even the total removal of Cl- from the extracellular solution had no negative influence on the Mg2 + uptake as long as HCO3- was present. Another result mitigating against a Mg2 + -2HCO3- cotransport is the significant reduction of Mg2 + influx in the HCO3--buffered high-KCl medium.
STEUER AND KEAT: PERIOPERATIVE USE OF METHOTREXATE 13. Katz JN, Larson MG, Ginsburg KS. Reconsideration of the risk of post arthroplasty infection in patients treated with methotrexate. Arthritis Rheum 1991; 34: 1624.
1. BOURA, A. L. A., GREEN, A. S., MCCOUBREY, A., LAURENCE, D. R., MOULTON, R., AND ROSENHEPAM, M. L.: Darenthin: hypotensive ageint of new type. Lancet 2: 17, 1959. PAGE, I. H., AND DUSTAN, H. P.: A new, potent antihypertensive drug. J.A.M.A. 170: 1265.
After one year, the overall difference in total costs between methotrexate and cyclosporine for 16 weeks of treatment and follow-up is relatively small.
Home prescribing information important safety information rheumatology home dermatology home treating ra with humira recent-onset ra' class secnav clinical efficacy in recent-onset ra long-standing ra' class secnav clinical efficacy in long-standing ra safety profile treating psa with humira treating as with humira growing experience mechanism of action myhumira program humira ® pen faqs abbott global humira patient site rheumatology dermatology 06g-64c-q352-3 look at the difference the humira support program can make 62% of humira + mtx– treated patients achieved acr50 at 1 year vs 46% with mtx alone p mean change in tss at 1 year primary endpoint ; was 7 for mtx-treated patients vs 3 in humira + mtx treatment group p das28 p the safety profile of humira is consistent across ra, psa, and as clinical trials 2-6 premier was a 2-year, multicenter, randomized, double-blind study n 799 ; evaluating the safety and efficacy of humira 40 mg sc every other week in subjects with moderate-to-severe early less than 3 years' duration ; rheumatoid arthritis ra ; who were methotrexate mtx ; -naï ve.
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A: control All patients had active RA despite treatment with stable methotrexate doses for 6 months prior to enrolment and were to remain on stable doses throughout the study. Concurrent use of stable doses of oral corticosteroids 10 mg day ; and or non-steroidal anti-inflammatory drugs was permitted, and folate supplementation was given. b: all infliximab doses given in combination with methotrexate and folate with some on corticosteroids and or non-steroidal anti-inflammatory drugs c: p 0.001, for each infliximab treatment group vs. control d: greater values indicate more joint damage. e: HAQ Health Assessment Questionnaire; greater values indicate less disability. Crohn's disease The safety and efficacy of infliximab were assessed in 108 patients with moderate to severe, active Crohn's disease Crohn's Disease Activity Index CDAI ; 220 400 ; in a randomised, doubleblinded, placebo-controlled, dose-response study. Of these 108 patients, 27 were treated with the recommended dosage of infliximab 5 mg kg. All patients had experienced an inadequate response to prior conventional therapies. Concurrent use of stable doses of conventional therapies was permitted, and 92% of patients continued to receive these medications. The primary endpoint was the proportion of patients who experienced a clinical response, defined as a decrease in CDAI by 70 points from baseline at the 4-week evaluation and without an increase in Crohn's disease medications or surgery for Crohn's disease. Patients who responded at week 4 were followed to week 12. Secondary endpoints included the proportion of patients in clinical remission at week 4 CDAI 150 ; and clinical response over time. At week 4, following a single dose of study medication, 22 27 81% ; of infliximab-treated patients receiving a 5 mg kg dose achieved a clinical response vs. 4 25 17% ; of the placebo-treated patients p 0.001 ; . Also at week 4, 13 27 ; of infliximab-treated patients achieved a clinical remission CDAI 150 ; vs. 1 25 4% ; of placebo-treated patients. A response was observed within 2 weeks, with a maximum response at 4 weeks. At the last observation at 12 weeks, 13 27 48% ; of infliximabtreated patients were still responding. The safety and efficacy were also assessed in a randomised, double-blinded, placebo-controlled study in 94 patients with fistulising Crohn's disease who had fistulae that were of at least 3 months' and methylcellulose.
51. Azrin MA, Mitchel JF, Bow LM, Alberghini TV, Peck R, Fram DB, Waters D, McKay RG. Effect of local delivery of heparin on platelet deposition during in vivo balloon angioplasty using hydrogel-coated balloons. Circulation. 1993; 88 suppl I ; : I-310. Abstract. 52. Kaplan AV, Kermode J, Grant G, Klein E, Vetter J, Hinohara T, Simpson JB. Intramural delivery of marker agent in ex vivo and in vivo models using a novel drug delivery sleeve. JAm Coll Cardiol. 1994; 23: 187A. Abstract. 53. Lincoff AM, Furst JG, Penn MS, Lee P, MacIsaac AI, Chisolm GM, Topol EJ. Efficiency of solute transfer by a microporous balloon balloon catheter in the porcine coronary model of arterial injury. J Coll Cardiol. 1994; 23: 18A. Abstract. 54. Barger AC, Beeuwkes R, Lainey LL, Silverman KJ. Hypothesis: vasa vasorum and neovascularization of human coronary arteries. N Engl J Med. 1984; 310: 175-177. Muller DWM, Topol EJ, Abrams GD, Ellis SG. Intramural methotrexate therapy for prevention of neointimal thickening after balloon angioplasty. JAm Coll Cardiol. 1992; 20: 460-466. Fram DB, Mitchel JF, Eldin AM, Waters DD, Norenberg FW, McKay RG. Intramural delivery of 3H-heparin with a new sitespecific drug delivery system -the D' catheter. JAm Coll Cardiol. 1994; 23: 186A. Abstract. 57. Carrozza JP, Kuntz RE, Levine MJ, Pomerantz RM, Fishman RF, Mansour M, Gibson CM, Senerchia CC, Diver DJ, Safian RD, Baim DS. Angiographic and clinical outcome of intracoronary stenting: immediate and long-term results from a large single-center experience. J Coll Cardiol. 1992; 20: 328-337. Kimura T, Nosaka H, Yokoi H, Iwabuchi M, Nobuyoshi M. Serial angiographic follow-up after Palmaz-Schatz stent implantation: comparison with conventional balloon angioplasty. J Coll Cardiol. 1993; 21: 1557-1563. Muller DWM, Ellis SG. Advances in coronary angioplasty: endovascular stents. CorArt Dis. 1990; 1: 438-448. Murphy JG, Schwartz RS, Edwards WD, Camrud AR, Vlietstra RE, Holmes DR. Percutaneous polymeric stents in porcine coronary arteries: initial experience with polyethylene terephthalate stents. Circulation. 1992; 86: 1596-1604. Lincoff AM, van der Giessen WJ, Schwartz RS, van Beusekom HMM, Serruys PW, Holmes DR, Ellis SG, Topol EJ. Biodegradable and biostable polymers may both cause vigorous inflammatory responses when implanted in the porcine coronary artery. JAm Coll Cardiol. 1993; 21: 179A. Abstract. 62. Zidar JP, Lincoff AM, Stack RS. Biodegradable stents. In: Topol EJ, ed. Textbook of Interventional Cardiology, 2nd ed. Philadelphia, Pa: WB Saunders Co; 1993: 787-802. 63. Lincoff AM, Furst JG, Ellis SG, Topol EJ. Sustained local drug delivery by a novel intravascular eluting stent to prevent restenosis in the porcine coronary artery. J Coll Cardiol. 1994; 23: 18A. Abstract. 64. Holmes DR, Edwards WD, Camrud AR, Jorgenson MA, Schwartz RS. Differential arterial response to stents in a porcine coronary model: exogenous fibrin vs polyurethane vs polyethylene terephthalate. J Coll Cardiol. 1993; 21: 179A. Abstract. 65. Fernandez-Ortiz A, Meyer BJ, Mailhac A, Chesebro JH, Badimon L, Hassinger N, Owen WG, Fuster V, Badimon JJ. Intravascular local delivery: an iontophoretic approach. Circulation. 1993; 88 suppl I ; : I-308. Abstract. 66. Dev V, Zeng H, Forrester J, Eigler N, Hickey AJ, Fishbein MC, Litvack F. Biodegradable microspheres for sustained drug delivery to the arterial wall. Circulation. 1993; 88 suppl I ; : I-311. Abstract. 67. Farb A, Carlson GC, Virmani R. In vivo local delivery and persistence of small and large particles following balloon angioplasty of atherosclerotic arteries: histologic confirmation. Circulation. 1993; 88 suppl I ; : I-310. Abstract. 68. Dev V, Zeng H, Forrester JS, Eigler N, Tian Y, Hickey AJ, Fishbein MC, Kupfer J, Litvack F. Microspheres for drug delivery to the arterial wall: a study of kinetics, toxicity, and effects of coroticosteroid loaded microspheres. J Coll Cardiol. 1994; 23: 19A. Abstract. 69. Robinson KA, Waksman R, Thomas C, Sigman SR, Cipolla GD, Britt B, Santoian EC, Tarazona N, King SB. The porous balloon catheter deposits gold microparticle suspension primarily at the site of medial fracture in balloon dilated pig coronary arteries. JAm Coll Cardiol. 1994; 23: 188A. Abstract. 70. Dichek DA, Neville RF, Zwiebel JA, Freeman SM, Leon MB, Anderson WF. Seeding of intravascular stents with genetically engineered endothelial cells. Circulation. 1989; 80: 1347-1353.
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WHO, promoting mental Health, Summary report, 2004 : who.int mental health evidence en promoting mhh 2 Wood, L. Healthy Communities: A review of relevant projects and feasibility for Healthway, 1999. Healthway: Perth: western Australia. 3 Syme, L. `Rethinking disease: where do we go from here? AEP, 1996, Vol. 6.5, pp 463-468 and methyldopa
Study objective: To determine the efficacy of methotrexate, vinblastine, and platinum chemother apy in patients with diffuse unresectable malignant mesothelioma. Design: Patients with histologically confirmed malignant mesothelioma were evaluated for treatment with methotrexate, vinblastine, and cisplatin chemotherapy. If the patient had preexisting hearing loss or neuropathy, or was significantly disabled eg, spending greater than half of the day in bed or a chair ; , cisplatin therapy was withheld. Setting: All patients were initially evaluated at the University of Washington Medical Center and received chemotherapy at the University of Washington or in the community. Interventions: Between 1990 and 1994, 17 patients received this chemotherapy. Ten patients received cisplatin, 100 mg m2 IV on day 1, methotrexate, 30 mg m2 IV on days 8, 15, and 22, and vinblastine, 3 mg m2 IV on days 8, 15, and 22, in 28-day cycles. One patient had carboplatin substi tuted for cisplatin due to preexisting hearing loss. Six patients received weekly methotrexate and vinblastine at the same doses without platinum. Measurements and results: Nine of the 17 53%; 95% confidence interval [CI], 28 to 77% ; patients responded, including two complete remissions, two partial remissions, and five regressions. Median time to progression is 8 months. The median survival time for all patients is 14 months. Projected 2-year survival is 35% 95% CI, 12 to 60% ; . Conclusions: Although the number of the patients in this study is small, the response rate and pro jected 2-year survival of 35% are better than thoseintypically reported for unresectable malignant mesothelioma. Further investigation is warranted confirmatory trials.
Ter 16 weeks of treatment. The economic evaluation studied direct and indirect costs during 16 weeks of treatment and 36 weeks of follow-up, producing estimates of 1-year cumulative total costs of treatment and methysergide.
Enable a truly strategic discussion of different budget options against scientific opportunities; progress and impact of activities; and the evolving research environment and public health needs. Previous JCB working groups on budget and governance have also suggested that, in between sessions, the Secretariat should provide information on budget status and any changes in stakeholders' commitments so as to facilitate JCB's response and support to TDR. This is important and the ERC supports the recommendation, with the proviso that these updates are brief and informative, and do not consume even more of the time of TDR staff than at present. The proposal to hold JCB sessions outside Geneva every other year was also made to redirect TDR's focus more effectively to the needs of DECs. The Secretariat has recently organized one-day briefing sessions, immediately before the JCB, for newly designated regional members of JCB. The ERC recommends institutionalizing these improvements, and further recommends bringing JCB even closer to countries' needs by fostering mechanisms that would give DECs a higher profile and more active role in JCB, e.g. in agenda setting and making presentations regarding regional needs.
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18. Wolfrom C, Fengler R, Hartmann R, Ingwersen A, Henze G: Toxicity of high dose methotrexate infusions with conventional and reduced leucovorin rescue. Klin Padiatr 202: 295, 1990 abstr ; 19. Chessells J, Leiper A, Rogers D: Outcome following late marrow relapse in childhood acute lymphoblastic leukemia. J Clin Oncol2: 1088, 1984 20. Rivera G, George SL, Bowman WP, Kalwinsky D, Ochs J, Dah1 GV, Hustu HO, Simone JV: Second central nervous system prophylaxis in children with acute lymphoblastic leukemia who relapse after elective cessation of therapy. J Clin Oncol1: 471, 1983 21. Fengler R, Hartmann R, Bode U, Janka G, Jiirgens H, Riehm H, Henze G: Risk of CNS relapse after systemic relapse of childhood acute lymphoblastic leukemia. Hamatol Bluttransfus 3351, 1990 22. Behrendt H, VanLeeuwen EF, Schuwirth C, Verkes RJ, Hermans J, VanDerDoes-VanDenBerg A, Vanwering ER: The significance of an isolated central nervous system relapse occurring as first relapse in children with acute lymphoblastic leukemia. Cancer 63: 2066, 1989 Sanders JE, Thomas ED, Buckner CD, Doney K Marrow transplantation for children with acute lymphoblastic leukemia in second remission. Blood 70: 324, 1987 Butturini A, Bortin MM, Rivera GK, Gale RP: Which treatment for childhood acute lymphoblastic leukaemia in second remission. Lancet 1: 429, 1987 Chessells JM, Leiper AD, Plowman PN, Levinsky R, Rogers DW, Blacklock H, Richards S, Festenstein H: Bone-marrow transplantation has a limited role in prolonging second marrow remission in childhood lymphoblastic leukaemia. Lancet 1: 1239, 1986 Niethammer D, Dopfer R, Klingebiel T, Riehm H, Schellong G, Henze G, Bender-Gotze C, Haas RJ, Schmitz N, Friedrich W, Ebell W, Stollmann B: Actual role and perspectives of BMT in children. Bone Marrow Transplant 4: 7, 1989 suppl4 ; 27. Pui CH, Bowman P, Ochs J, Dodge RK, Rivera G K Cyclic combination chemotherapy for acute lymphoblastic leukemia recurring after elective cessation of therapy. Med Pediatr Oncol 16: 21, 1988 and metolazone.
Pulse pressure mmHg ; 50 to CRP mg L ; 4.21 to 12.52 PTH pg ml ; 150 to 300 PTH pg ml ; 100 PO4 mmol L ; 1.13 to 1.78 Ca mmol L ; 2.1 to 2.37 Ca PO4 mmol2 L2 ; 4.5 bALP g L ; 6.99 to 11.19 OPG pg ml ; 1550.4 to 2438.4 sRANKL pmol L ; 0.136 to 0.298.
The cDNAs that encode the selected Ets factors were cloned into the PCI CMV expression vector Promega ; and were verified by DNA sequencing. ERP Ets-related protein ; and the 3 NERF isoforms were obtained in our laboratory.17, 25 Sap-1 and Elk-1 were gifts from Roger Davis University of Massachusetts, Worcester, Mass Ets-1 and Ets-2, Dan Tenen Beth Israel Deaconess Medical Center, Boston, Mass ELF-1, Jeffrey Leiden University of Chicago, Chicago, Ill and TEL, Todd Golub Dana Farber Cancer Center, Boston, Mass ; . The mouse Flt-1 promoter luciferase construct was a gift from Bill Aird Beth Israel Deaconess Medical Center, Boston, Mass ; . The urokinase promoter Ets site was constructed by ligating a double-stranded oligonucleotide that encoded the urokinase promoter Ets-binding site in a PGL3 vector that contained the cFos 56 minimal promoter, which we have previously used as a minimal reporter.17, 25 The LacZ reporter constructs are shown in Figure 1B and include the 2.1-kb promoter and the 10.0 kb 5 half of the first intron up to and including the 1.7-kb intronic enhancer construct No. 1 ; , the 2.1 kb HindIII-HindIII, the 2.1-kb promoter together with the 1.7-kb XhoI-KpnI intronic enhancer construct No. 2 ; , the 1.7-kb intronic enhancer with the HSV-tk minimal promoter construct No. 3 ; , and the promoter alone construct No. 4 ; . Deletion constructs of the Tie2 gene were further subcloned into the PGL3 luciferase vector Promega ; and are shown in Figure 1B and 1C. Point mutations were made with a site-directed mutagenesis kit QuikChange, Stratagene ; . The expression plasmid used for overexpression of selected Ets factors was the PCI vector Promega and micafungin.
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Joseph Amato `91 and Amy Commisso were married in St. Margaret Mary Church, Woodbridge, ON, 3 June 2000. Amy teaches primary grades for the Toronto Public School Board in Kingsview, ON; Joseph is a lawyer with CIBC's commercial mortgage division. Lisa Ball `91 received her LLB from the U. of Ottawa in June 1999. She is articling with a law firm in Timmons, ON, where she and her husband of five years, Joe Barazzutti, reside as she awaits her call to the bar. Mary Elizabeth Bennett `89 is a Senior Editor for CCH Canadian Ltd. in Toronto. Rose Marie Sbrolla Braden `85 her husband, Mike, and their sons, Max, 9, Jake, 6, Teddy 4, and Michael, 2 3 4, continue to live in Ottawa, where Rosie is a lawyer with the Department of Justice Child Support Team, and Mike, pursuing a change in career from the law, recently completed the program at Teachers' College, U. of Ottawa. Mike and Rosie recently celebrated their 10th wedding anniversary with a trip to Tobago. Mary Warriner Brown `51 was invested as an Honorary Fellow of the U. of St. Michael's College at the 12 June Convocation Baccalaureate Mass. Mary's extensive volunteer involvement in the work of the U of T, St. Michael's, the Archdiocese, the civic community, and her contribution to society through her work for the Government of Ontario were highlighted in the citation read on the occasion. Mary is at present the President of J.P. Brown & Associates, the firm founded by her late husband Pat `51. Richard `95 and Marjorie Small Budnikas `85 live in Vancouver, BC and welcomed their first child, Sophia, 9 February 2000. Marjorie is doing private tutoring in French and English; Richard teaches high school and is head of technology education in his school. Fred `75 and Anne Ryan Butzen `74 continue to live in Chicago, IL; their five children are thriving: Ivan in the Marines, Marion in college, George and Catherine in high school, and Richard, 2 1 4, at home looking after Anne! Fred is coding for a software company that does telephone applications, and has written another book, The Linux Network, published by IDG Books and now translated into Chinese and Hungarian. Cathy Reid Callaghan `80, her husband, Tom U of T Phys.Ed. ; , and their four children, Liam, 8, Brigid, 7, Ciaran, 5, and Eamon, 2, live in Newmarket, ON, where Cathy is a partner in the law firm of Hill Hunter; Richard teaches at Cardinal Carter High School in Aurora, ON. Cathy reports that she and the family "regularly come to St. Mike's for the Annual Santa Claus Parade [Mass and pre-parade hot chocolate cookies] and enjoy seeing other grads there." Edith Colantonio Chesser `85, her husband Hugh U of T Engineering and SMC resident ; and their children, Ryan, grade 6, Erica, grade 4, and Stefanie, grade 2, have moved from Winnipeg, MB to Richmond Hill, ON. Hugh has a position with the U of T's Institute for Aerospace. Dr. Claudia Clausius `78 received her MA `79 and PhD `89 from the U of T and is at present Professor and Academic Dean of King's College in the U. of Western Ontario; she was formerly a Professor at Concordia U., Montreal, PQ. Claudia and her husband, Michael Crawford, have two children, Katharina and Nicholai. Rick Costanzo `92 and Pamela Gould were married 5 November 1994 and welcomed their daughter, Madelyn Edith, 6 March 1998; they now live in Guelph, ON. Rick was in Sales Management for the Business Services Division of AT&T Canada for several years before accepting the position of Regional Manager for Research in Motion in July 1998. Greta DeLonghi `83 has returned to The Kitchener-Waterloo Record as a part-time copy editor; one of her co-workers is Melinda Marks `73. Greta, her husband, Guntis Obrascous, and their two children, Leon, 5, and Felix, 3, live in Guelph, ON Carla DeSantis `88 and Reni Caccamo `88 welcomed their second child, Noah Reni, 5 November 1999, a brother for Luke, 5. Carla will be completing a SSHRC Post-doctoral Fellowship at the U of T after maternity leave. Carla presented a paper, "Translation in Teaching Latin: a 14thCentury Italo-Latin Grammar", at the "Teaching, Learning, and Using Latin in the Middle Ages" Conference held at the U of T March 1999. Reni continues in his position as Director of Logistics at Apotex International. Sr. Jacqueline de Verteuil, C.S.J. `75 is a local consultant for the Diploma in Ministry Program at St. Francis Xavier U. in Antigonish, NS. Meera Dey Montell `91 and Scott Montell were married 11 September 1999 in Madison, NJ; Alexandra Ahr Dunn `91 was the matron of honour. Meera and Scott are graduates of Fordham Law School, where they first met; they now live in Brooklyn, NY. Both are practicing Law; Meera is an attorney with Children's Services. Katie Di Genova `94 and her husband, Daniel De Luca, welcomed their second child, Selina, 28 January 2000. John DiMarco `89 received the annual "Dean's Outstanding Technical Service Award" from the Dean of the Faculty of Arts and Science of the U of T; John is the Computer Systems Manager for the U of T's Department of Computer Science. DiTomaso Annual "St. Mike's Bash": Katie DiTomaso `00 reports that the 3rd annual St. Michael's bash also known, she notes, as "A MidSummer St. Mike's Dream"! ; held 22 July `00 at the DiTomaso home in Midland, ON, was a great success. Other SMCers and U of Ters in attendance, or on the "Dream Team": Katie's brother, Mike `02 and her parents, Guy `72 and Mary Grace PHE'73 Loretto College resident ; DiTomaso; Nikki Doria `00, Andrea Venditti `00, Beth Bray PHE `81, and "hopefuls" Mary Kubesh `01, Mike Colella `02, Brian "Bitter" Harvey `02, Mike "Screech" Hatch `03, Adrian Rasekh `03, and Aisling Moss PHE `01. Plans are already underway for the 4th annual DiTomaso SMC U of T gathering, 21 July 2001! Katie has entered firstyear Law like father like daughter ; at the U of Western Ontario, London, ON. Driscoll Report: Dan `55 and Sylvia Rinaldi Driscoll `56 attended SMC's Spring Reunion last June and provided us with the following information about their three SMC grad children: Mary Pat Ambrosino `82, her husband Gary and their three children, Rebecca, Megan, and Sarah, live in Scotia, NY, where Mary Pat is a Nutritionist in the local hospital; Cathy `85 and Michael Sangster were married in 1998 and with their first child, Sylvia Danielle, born 9 Sept. `99, live in Halifax, NS, where Cathy is a tenured Associate Professor of Management at St. Mary's University. Last April Cathy received the 1999 Academy of Business Administration's Teaching Excellence Award at its conference in Vancouver, BC. The ABA is an international body of academics across all business disciplines and makes one award each year based on the innovative and exemplary performance of a teacher. Dan Jr. `87 and his wife, Jeanine, welcomed their first child, a son, Daniel, 23 June of this year. Dan works with British Airways in New York City; he and the family live in Middle Village, NY. Katherine Hauke DuGarm `82 and her husband, Delano, have moved from Arlington, VA to Woodbury MN. Kathy has taken a new position as full-time programmer with St. Croix Systems in St. Croix, Wisconsin. Of her new parish she writes, "St. Ambrose is a welcoming place. The liturgy and religious education staff are good, working together to create spiritual and social community." Alix Ahr Dunn `91 and her husband, John, welcomed their first child, John Eugene "Jack" ; Dunn, 6lbs, 10 1 oz, 19 1 2 inches tall, 17 Feb. 2000. Alix is Vice-President, Account Supervisor, with the Ketchum public relations agency in New York City, where John is Senior Vice-President, Marketing and Product Development, for on2 . The Dunns live in Pelham Manor, NY.
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Within the main river valley, the FPA boundary is intended to coincide with the bluff edge or functional ridgeline behind which development would be relatively unobtrusive on the open space character of the valley floor. This FPA is identified by the JPA as the area where planning and acquisition efforts for the Park are to be directed. The boundaries of the FPA were first established in 1981 by the Pekarek Study, and at that time the planning area extended only to Lake Sutherland. The FPA was extended eastward in 1988 by the SANDAG San Dieguito River Valley Regional Open Space Park Plan Executive Committee the predecessor to the JPA ; to include the entire San Dieguito River drainage, as well as several major tributary canyons. Boden Canyon, a 1, 500-acre area located immediately to the west of Pamo Valley, was added to the FPA by the JPA in 1990. In 1993, the JPA once again expanded the FPA boundary, this time eastward to incorporate the entire 11, 000-acre Rutherford Ranch, which includes the eastern and western slopes of Volcan Mountain as well as a portion of the San Felipe Valley. The inclusion of the Rutherford Ranch into the FPA establishes a link from the ocean to the desert and the Anza Borrego State Park. The FPA boundary is not intended to establish a static demarcation between potentially developable and undevelopable land. It serves instead to identify those areas where improper development could significantly impact the existing character of the river valley. In addition, it is within the FPA that acquisition funds should be directed, and where park amenities such as the "Coast to Crest Trail" will be established. As more specific planning efforts are undertaken, in the form of master plans for the individual landscape units within the Park planning area, it may become apparent that the FPA boundary should be expanded or constricted to more accurately reflect the viewshed of the river valley. Ownerships Within The Focused Planning Area The properties included within the FPA represent both publicly and privately owned land. Approximately 60 percent of the area is publicly owned, with the largest percentage owned by the City of San Diego Water Utilities Department. The remaining areas of publicly owned land include lands owned by the U.S. Forest Service Cleveland National Forest ; , the Bureau of Land Management, the State of California, the County of San Diego, the cities of Del Mar and Escondido, and the Olivenhain Municipal Water District. Approximately 800 acres of land located east of Lake Sutherland are owned by the Mesa Grande Band of Mission Indians. Privately owned lands, which make up the remainder of the planning area, occur throughout the FPA and range from one-acre ownerships to ownerships in excess of 1, 000 acres and midodrine.
Agonists similar to, serotonin receptor subtypes, frontal cortex rats ; , 480 Pituitary-adrenocortical axis, stress-opioid interactions, role in rats ; , 555 Pituitary gland, prostaglandin E and gastric secretion rats ; , 713 Plaque-forming cells, beta-mediated response mice ; , 527 Plasminogen activator, tissuetype, recombinant DNA and rabbits ; , 146 Pollock, G. D., see Hayes, J. S., 633 Polyacrylstarch, microparticles, dextranase in, duration of action rats ; , 705 Polyglutamate methotrexate, reticulocyte synthesis and rats ; , 43 methotrexate metabolites, skin, liver and blood rats, mice ; , 242 Pons, reticular formation, neostigmine microinjection into, desynchronized sleep signs cats ; , 173 Portal vein, photoaffinity labeling rats ; , 137 Portoghese, P. S., see DeLander, G. E., 91 and methotrexate.
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9: 00 a.m. Conceptual Design of Nuclear Battery Using Semiconductor, Won Jun Chang, Soon Heung Chang KAIST ; 9: 30 a.m. Sensitivity of the Fixed Point Formulation to Density for Large Sample PGNAA, Hatice Akkurt, James Paul Holloway Univ of Michigan ; 10: 00 a.m. Sensitivity of the Fixed Point Iteration to Neutron Source Spectrum for Large Sample PGNAA, Hatice Akkurt, James Paul Holloway Univ of Michigan ; 10: 30 a.m. An Improved High Pressure Xenon Ambient Temperature GammaRay Spectrometer, R. A. Sigg Westinghouse SRS ; WEDNESDAY, JUNE 16, 2004 1: 00 P.M. Demonstration of Sensitivity and Uncertainty Analysis Tools and Methodology TSUNAMI ; Within SCALE5--II: Tutorial, sponsored by NCSD. Chair: Sedat Goluoglu ORNL ; Monongahela 1: 00 p.m. The use of TSUNAMI to determine areas of applicability of benchmarks will be demonstrated in two sessions in tutorial demonstration format. TSUNAMI consists of several sensitivity and uncertainty analysis tools within SCALE5, which is planned to be publicly available by the summer of 2004. These tools allow analysis of critical experiments to assess applicability to the validation of a particular application through several integral parameters. The cross-section uncertainties are carried through the analysis and utilized in determining the applicability of benchmark experiments and assessing the penalty one must exert due to limited applicability of the existing critical experiments. Integrated Risk-Informed Decision MakingPaper Panel, sponsored by OPD. Chair: Mark Reinhart NRC ; Alleghany PAPER: 1: 00 p.m. Day-to-Day PRA Use at a Nuclear Power Plant, John F. Helfenberger and mifeprex.
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