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Expression pattern of mouse 1, 3GalNAc-T gene in mouse tissues Expression levels of the mouse 1, 3GalNAc-T gene in 12 mouse tissues were examined by Northern blotting. Among tissues examined, strong gene expression was observed in brain, heart, kidney, liver, skin and testis, and low level expression was observed in lung Fig.3. RESULTS: 150 students completed the station in 2004 as MS2s and 151 students completed it as MS4s. MS2 performance was superior on most components of the lung exam see table, p 0.001 ; except for two items: Bplaced stethoscope against my skin p 0.48 ; and Ballowed for a full cycle of breathing p 0.092 ; . CONCLUSIONS: When examining a standardized patient with symptoms of pneumonia, performance of physical exam skills by a single cohort of medical students was worse during their MS4 year as compared to their MS2 year. Whether the difference reflects better Btest taking skills by MS2s, better efficiency by MS4s, or erosion of clinical skills by experiences during the clerkships is unknown C.A. Gunawan1, P.N. Harijanto2. 1Mulawarman University School of Medicine A. Wahab Sjahranie General Hospital, Samarinda, Indonesia; 2 Sam Ratulangi University School of Medicine Bethesda Hospital, Tomohon, Indonesia Background: Malaria remains the most important parasitic disease in the world, endemic in 100 countries with approximately 3 million deaths every year. The most frequent complications found in South East Asia are cerebral malaria, malaria with jaundice and acute renal failure. In Minahasa, North Sulawesi, Indonesia 54.2 % of severe malaria treated at hospitals were malaria with jaundice. Objectives. To know the features of severe malaria with jaundice patients treated at A. Wahab Sjahranie General Hospital, Samarinda. Methods: A prospective-observational study was performed on severe malaria with jaundice patients treated at the Department of Internal Medicine of A. Wahab Sjahranie General Hospital, Samarinda during January 2004 to December 2005. Inclusion criteria were patients 15 years old with positive blood smear for asexual stage of Plasmodium falciparum and total bilirubin level 3.0 mg dL. Patients with history of chronic liver diseases were excluded. Data collected were vital signs, level of consciousness GCS ; , CBC, random blood glucose, ureum, creatinine, SGOT, SGPT, total bilirubin, conjugated bilirubin, unconjugated bilirubin. Anti malarial drug given was parenteral quinine 10 mg kg body weight 8 hours for at least 48 hours, continued with sulfate quinine tablet if patients could take oral medicines, until 7th day. Results: There were 112 severe malaria patients treated during 2 years and 58 % of them 65 patients ; were malaria with jaundice, consisting of 56 males 86.2 % ; and 9 females 13.8 % ; . Patients ages` were 15 - 58 years with mean age 31.0 years. Malarial blood smear showed P. falciparum + ; 26.2 %, + ; 21.5 %, + ; 27.7 %, + ; 24.6 %. Distribution of patients according to total bilirubin level was as follows: 3.1 - 5.0 mg dL 13.8 %, 5.1 - 10.0 mg dL 36.9 %, 10.1 - 20.0 mg dL 23.1 %, 20.1 - 30.0 mg dL 15.4 %, 30 mg dL 10.8 %. Total bilirubin level ranged from 3.1 to 43.1 mg dL with mean value 14.01 mg dL, mean conjugated bilirubin level 8.06 mg dL 1.3 - 30.1 ; , mean unconjugated bilirubin level 5.95 mg dL 0.8 - 20.5 ; . Mean SGOT level was 149.3 IU L 11 - 753 ; , mean SGPT level was 125.1 IU L 18 - 626 ; . Mean SGOT SGPT ratio was 1.19. Almost all jaundiced patients 83.1 % ; were accompanied with other complication s ; such as cerebral malaria, acute renal failure. Three patients had melena and 1 patient with DIC. Overall mortality of jaundiced patients was 38.5 %. The mortality rate of patients with total bilirubin 3.1 - 5.0, 5.1 - 10.0, 10.1 - 20.0, 20.1 - 30.0, mg dL were 11.1 %, 25.0 %, 40.0 %, 50.0 %, 85.7 % respectively. Conclusions: Severe malaria with jaundice is a frequent complication found 58 % ; in Plasmodium falciparum infection. Total bilirubin level can rise 40 mg dL with mean conjugated bilirubin level is higher than mean uncojugated bilirubin level 8.06 vs 5.95 mg dL ; . Serum transaminases are elevated as high as 700 IU L with mean SGOT level is higher than mean SGPT level 149.3 vs 125.1 ; . Liver parenchymal disorder and cholestasis seems to play a more important role, compared with hemolysis, in the development of jaundice in severe malaria patients. Overall mortality rate of jaundiced patients is 38.5 %. The higher the total bilirubin level, the higher the mortality rate 80 % in patients with total bilirubin level 30 mg dL.

149; do not take chlorpheniramine if you have taken a monoamine oxidase inhibitor maoi ; such as isocarboxazid marplan ; , phenelzine nardil ; , or tranylcypromine parnate ; in the last 14 days.
Ovaries A pair of female sex glands that store and release ova see ovum ; and produce the sex hormones estrogen and progesterone see Female Anatomy, p. 364 ; . ovulation The release of an ovum from an ovary. ovum Reproductive egg cell produced by the ovaries. partially breastfeeding See breastfeeding. pelvic inflammatory disease See Pelvic inflammatory disease, Appendix B, p. 321. pelvic tuberculosis Infection of the pelvic organs by tuberculosis bacteria from the lungs. pelvis The skeletal structure located in the lower part of the human torso, resting on the legs and supporting the spine. In females, also refers to the hollow portion of the pelvic bone structure through which the fetus passes during birth. penis The male organ for urination and sexual intercourse see Male Anatomy, p. 367 ; . perforation A hole in the wall of an organ or the process of making the hole, as with a medical instrument. placenta The organ that nourishes a growing fetus. The placenta afterbirth ; is formed during pregnancy and comes out of the uterus within a few minutes after the birth of a baby. postpartum After childbirth; the first 6 weeks after childbirth. pre-eclampsia Hypertension with either excess protein in the urine, or local or generalized swelling, or both but without convulsions ; after 20 weeks of pregnancy. May progress to eclampsia. premature birth A birth that occurs before 37 weeks of pregnancy. preventive measures Actions taken to prevent disease, such as washing hands or providing drugs or other therapy. progesterone A steroid hormone that is produced by the ovary after ovulation. Prepares the endometrium for implantation of a fertilized egg ovum ; , protects the embryo, enhances development of the placenta, and helps prepare the breasts for breastfeeding. progestin progestogen ; Any of a large group of synthetic drugs that have effects similar to those of progesterone. Some are used in hormonal contraceptives. prolonged bleeding See vaginal bleeding. prolonged rupture of membranes Occurs when the fluid-filled sac surrounding a pregnant woman's fetus breaks 24 hours or more before delivery of the infant. prophylaxis See preventive measures. prostate Male reproductive organ where some of the semen is produced see Male Anatomy, p. 367 ; . puerperal sepsis Infection of the reproductive organs during the first 42 days postpartum puerperium ; . pulmonary embolism See Pulmonary embolism, Appendix B, p. 321. pulmonary hypertension Continuous hypertension in the pulmonary artery, impeding blood flow from the heart to the lungs. purulent cervicitis Inflammation of the cervix accompanied by a pus-like discharge. Often indicates infection with gonorrhea or chlamydia. pus A yellowish-white fluid formed in infected tissue. retinopathy Disease of the retina nerve tissue lining the back of the eye ; , including damage to the small blood vessels to the retina from long-standing diabetes. ruptured ectopic pregnancy See Ruptured ectopic pregnancy, Appendix B, p. 321. schistosomiasis A parasitic disease caused by a flatworm living in a snail host. People become infected while wading or bathing in water containing larvae of the infected snails and phenylpropanolamine.

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